All journal publications (1904-2010)

Meijer, O.C., De Kloet, E.R. , Coregulators in CNS Function and Disease, Nuclear Receptor Coregulators and Human Diseases: World Scientific Publishing, pp. 383-408.

de Kloet, E.R. , Commentary: neuroendocrine basis, Prog Brain Res, vol. 167, pp. 53-62.

de Rijk, R.H., van Leeuwen, N., Klok, M.D., Zitman, F.G. , Corticosteroid receptor-gene variants: Modulators of the stress-response and implications for mental health, Eur.J Pharmacol, vol. 585, no. 2-3, pp. 492-501.

Korobko, O.B., Glas, C.A.W., Bosker, R.J., Luyten, J.W. , Comparing the Difficulty of Examination Subjects with Item Response Theory, Journal of Educational Measurement, vol. 45, no. 2, pp. 139-157.

Oitzl, M.S. , Commentary: behavioral phenotype, Prog.Brain Res., vol. 167, pp. 111-117.

Pedotti, P., t Hoen, P.A., Vreugdenhil, E., Schenk, G.J., Vossen, R.H., Ariyurek, Y., de Hollander, M., Kuiper, R., van Ommen, G.J., den Dunnen, J.T., Boer, J.M., de Menezes, R.X. , Can subtle changes in gene expression be consistently detected with different microarray platforms?, BMC Genomics, vol. 9, pp. 124.

Schwabe, L., Dalm, S., Sch„chinger, H., Oitzl, M.S. , Chronic stress modulates the use of spatial and stimulus-response learning strategies in mice and man, Neurobiol.Learn.Mem., vol. 90, no. 3, pp. 495-503.

Wust, S., Kumsta, R., de Rijk, R.H., Entringer, S., van Rossum, E.F.C., Koper, J.W., Hellhammer, D.H. , Corticosteroid receptor gene variants and stress reactivity: Implications for the development of depression, Journal of Affective Disorders, vol. 107, pp. S39-S39.

Berry, A., Greco, A., Giorgio, M., Pelicci, P.G., De Kloet, E.R., Alleva, E., Minghetti, L., Cirulli, F. , Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice, Experimental Gerontology, vol. 43, no. 3, pp. 200-208.

Boekhoorn, K., Sarabdjitsingh, A., Kommerie, H., de Punder, K., Schouten, T.G., Lucassen, P.J., Vreugdenhil, E. , Doublecortin (DCX) and doublecortin-like (DCL) are differentially expressed in the early but not late stages of murine neocortical development, J Comp Neurol., vol. 507, no. 4, pp. 1639-1652.

Schaaf, M.J., Champagne, D.L., van Laanen, I, van Wijk, D.C., Meijer, A.H., Meijer, O.C., Spaink, H.P., Richardson, M.K. , Discovery of a functional glucocorticoid receptor beta-isoform in zebrafish, Endocrinology, vol. 149, no. 4, pp. 1591-1599.

t Hoen, P.A., Ariyurek, Y., Thygesen, H.H., Vreugdenhil, E., Vossen, R.H., de Menezes, R.X., Boer, J.M., van Ommen, G.J., den Dunnen, J.T. , Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms, Nucleic Acids Res., vol. 36, no. 21, pp. e141.

Topic, B., Oitzl, M.S., Meijer, O.C., Huston, J.P., Silva, M.A.D. , Differential Susceptibility to Extinction-Induced Despair and Age-Dependent Alterations in the Hypothalamic-Pituitary-Adrenal Axis and Neurochemical Parameters, Neuropsychobiology, vol. 58, no. 3-4, pp. 138-153.

Jacobs, G., Kamerling, I, de Kam, M., de Rijk, R.H., van Pelt, J., Zitman, F.G., van Gerven, J. , Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron, J.Psychopharmacol..

van Veen, J.F., Van Vliet, I.M., de Rijk, R.H., van Pelt, J., Mertens, B., Zitman, F.G. , Elevated alpha-amylase but not cortisol in generalized social anxiety disorder, Psychoneuroendocrinology, vol. 33, no. 10, pp. 1313-1321.

Wust, S., Kumsta, R., de Rijk, R.H., Entringer, S., van Rossum, E.F.C., De Kloet, E.R., Hellhammer, D.H., Koper, J.W. , Glucocorticoid and mineralocorticoid receptor gene variants are associated with ACTH, cortisol and cardiovascular responses to psychosocial stress, International Journal of Psychology, vol. 43, no. 3-4, pp. S063, 195-195.

Abildayeva, K., Berbee, J.F., Blokland, A., Jansen, P.J., Hoek, F.J., Meijer, O.C., Lutjohann, D., Gautier, T., Pillot, T., De Vente, J., Havekes, L.M., Ramaekers, F.C., Kuipers, F., Rensen, P.C., Mulder, M. , Human apolipoprotein C-I expression in mice impairs learning and memory functions, J Lipid Res., vol. 49, no. 4, pp. 856-869.

Catusse, J., Spinks, J., Mattick, C., Dyer, A., Laing, K., Fitzsimons, C.P., Smit, M.J., Gompels, U.A. , Immunomodulation by herpesvirus U51A chemokine receptor via CCL5 and FOG-2 down-regulation plus XCR1 and CCR7 mimicry in human leukocytes, European Journal of Immunology, vol. 38, no. 3, pp. 763-777.

Schmidt, M.V., Sterlermann, V., Trumbach, D., Datson, N.A., Weber, P., Holsboer, F., Muller, M.B. , Individual susceptibility to chronic stress is modulated by AMPA receptor function, International Journal of Neuropsychopharmacology, vol. 11, pp. 212-212.

Ter Horst, J.P., Loscher, J.S., Pickering, M., Regan, C.M., Murphy, K.J. , Learning-associated regulation of polysialylated neural cell adhesion molecule expression in the rat prefrontal cortex is region-, cell type- and paradigm-specific, Eur.J.Neurosci., vol. 28, no. 3, pp. 419-427.

van der Veen, R., Koehl, M., Abrous, D.N., de Kloet, E.R., Piazza, P.V., Deroche-Gamonet, V. , Maternal environment influences cocaine intake in adulthood in a genotype-dependent manner, PLoS One, vol. 3, no. 5, pp. e2245.

de Kloet, E.R. , Nothing is carved in stone, Tijdschr Psychiatr, vol. 50, no. 12, pp. 781-3.

Veen, G., van Vliet, I, de Rijk, R.H., Zitman, F.G. , Need for alternative ways of phenotyping of mood, anxiety, and somatoform disorders in biological research, Prog.Brain Res., vol. 167, pp. 277-280.

Verzijl, D., Storelli, S., Scholten, D.J., Bosch, L., Reinhart, T.A., Streblow, D.N., Tensen, C.P., Fitzsimons, C.P., Zaman, G.J., Pease, J.E., de Esch, I, Smit, M.J., Leurs, R. , Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors, Journal of Pharmacology And Experimental Therapeutics, vol. 325, no. 2, pp. 544-555.

Frasca, A., Fumagalli, F., Ter Horst, J.P., Racagni, G., Murphy, K.J., Riva, M.A. , Olanzapine, but not haloperidol, enhances PSA-NCAM immunoreactivity in rat prefrontal cortex, Int.J.Neuropsychopharmacol., vol. 11, no. 5, pp. 591-595.

Drexhage, R.C., Padmos, R.C., de Wit, H., Versnel, M.A., Hooijkaas, H., van der Lely, A.J., van Beveren, N., de Rijk, R.H., Cohen, D. , Patients with schizophrenia show raised serum levels of the pro-inflammatory chemokine CCL2: Association with the metabolic syndrome in patients?, Schizophrenia Research, vol. 102, no. 1-3, pp. 352-355.

Smarius, L.J., Jacobs, G.E., Hoeberechts-Lefrandt, D.H., de Kam, M.L., van der Post, J.P., de Rijk, R.H., van Pelt, J., Schoemaker, R.C., Zitman, F.G., Van Gerven, J.M., Gijsman, H.J. , Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa, J Psychopharmacol., vol. 22, no. 4, pp. 426-433.

van der Laan, S., Meijer, O.C. , Pharmacology of glucocorticoids: Beyond receptors, Eur.J Pharmacol, vol. 585, no. 2-3, pp. 483-491.

De Kloet, E.R., Oitzl, M.S., Vermetten, E. , Stress hormones and post traumatic stress disorder basic studies and clinical perspectives, Progress in Brain Research, vol. 1st, no. xviii, 320, Amsterdam, Elsevier, pp. 1-320.

Brinks, V., de Kloet, E.R., Oitzl, M.S. , Strain specific fear behaviour and glucocorticoid response to aversive events: modelling PTSD in mice, Prog Brain Res, vol. 167, pp. 257-61.

Datson, N.A. , Scaling down SAGE: from miniSAGE to microSAGE, Curr.Pharm.Biotechnol., vol. 9, no. 5, pp. 351-361.

De Bosscher, K., Van Craenenbroeck, K., Meijer, O.C., Haegeman, G. , Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems, Eur.J Pharmacol, vol. 583, no. 2-3, pp. 290-302.

Spijker, A.T., Hoencamp, E., van Rossum, E., de Rijk, R.H., Haffmans, J., Blom, M. , Several polymorphisms of the glucocorticoid receptor gene (NR3C1) and their associations with bipolar disorder, Journal of Affective Disorders, vol. 107, pp. S74-S75.

Schmidt, M.V., Sterlemann, V., Trumbach, D., Datson, N.A., Weber, P., Ganea, K., Liebl, C., Muller, M.B. , The genetic basis of individual vulnerability to chronic stress: role of AMPA receptors, European Neuropsychopharmacology, vol. 18, pp. S16-S16.

2007

Schmidt, M.V., Oitzl, M., Steenbergen, P., Lachize, S., Wurst, W., Muller, M.B., de Kloet, E.R., Meijer, O.C. , Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function, Brain Res, vol. 1174, pp. 1-6.

Conway-Campbell, B.L., McKenna, M.A., Wiles, C.C., Atkinson, H.C., de Kloet, E.R., Lightman, S.L. , Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone, Endocrinology, vol. 148, no. 11, pp. 5470-7.

Morsink, M.C., Van Gemert, N.G., Steenbergen, P.J., Joels, M., De Kloet, E.R., Datson, N.A. , Rapid glucocorticoid effects on the expression of hippocampal neurotransmission-related genes, Brain Res, vol. 1150, pp. 14-20.

Schoonman, G.G., Evers, D.J., Ballieux, B.E., de Geus, E.J., de Kloet, E.R., Terwindt, G.M., van Dijk, J.G., Ferrari, M.D. , Is stress a trigger factor for migraine?, Psychoneuroendocrinology, vol. 32, no. 5, pp. 532-8.

Veenema, A.H., de Kloet, E.R., de Wilde, M.C., Roelofs, A.J., Kawata, M., Buwalda, B., Neumann, I.D., Koolhaas, J.M., Lucassen, P.J. , Differential effects of stress on adult hippocampal cell proliferation in low and high aggressive mice, J Neuroendocrinol, vol. 19, no. 7, pp. 489-98.

Berry, A., Capone, F., Giorgio, M., Pelicci, P.G., de Kloet, E.R., Alleva, E., Minghetti, L., Cirulli, F. , Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice, Exp Gerontol, vol. 42, no. 1-2, pp. 37-45.

Sibug, R.M., Datson, N., Tijssen, A.M., Morsink, M., de Koning, J., de Kloet, E.R., Helmerhorst, F.M. , Effects of urinary and recombinant gonadotrophins on gene expression profiles during the murine peri-implantation period, Hum Reprod, vol. 22, no. 1, pp. 75-82.

de Jong, I.E., Oitzl, M.S., de Kloet, E.R. , Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner, Behav Brain Res, vol. 177, no. 2, pp. 329-39.

de Kloet, E.R., De Rijk, R.H., Meijer, O.C. , Therapy Insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression?, Nat Clin Pract Endocrinol Metab, vol. 3, no. 2, pp. 168-79.

Schenk, G.J., Engels, B., Zhang, Y.P., Fitzsimons, C.P., Schouten, T., Kruidering, M., de Kloet, E.R., Vreugdenhil, E. , A potential role for calcium / calmodulin-dependent protein kinase-related peptide in neuronal apoptosis: in vivo and in vitro evidence, Eur J Neurosci, vol. 26, no. 12, pp. 3411-20.

Oomen, C.A., Mayer, J.L., de Kloet, E.R., Joels, M., Lucassen, P.J. , Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress, Eur J Neurosci, vol. 26, no. 12, pp. 3395-401.

Han, F., Ozawa, H., Matsuda, K. I, Lu, H., De Kloet, E.R., Kawata, M. , Changes in the expression of corticotrophin-releasing hormone, mineralocorticoid receptor and glucocorticoid receptor mRNAs in the hypothalamic paraventricular nucleus induced by fornix transection and adrenalectomy, J Neuroendocrinol, vol. 19, no. 4, pp. 229-38.

Enthoven, L. , Early life experience: neuroendocrine adaptations to maternal absence, , vol. PhD: Leiden University.

Morsink, M.C. , Glucocorticoid control of gene transcription in neural tissue, , vol. PhD: Leiden University.

de Jong, I.E.M. , Vulnerability to cocaine: role of stress hormones, , vol. PhD: Leiden University.

Oitzl, M.S. , Avoidance, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 297-301.

Glas, C.A.W., Korobko, O.B. , A Marginal Maximum Likelihood Procedure for an IRT Model with Single-Peaked Response Functions, OMD Progress Report 07-01, vol. 07, no. 01, pp. 1-10.

Meijer, O.C., De Kloet, E.R., McEwen, B.S. , Corticosteroid Receptors, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 594-605.

Brinks, V., van der Mark, M.H., de Kloet, E.R., Oitzl, M.S. , Differential MR/GR activation in mice results in emotional states beneficial or impairing for cognition, Neural Plast, vol. 2007, pp. 90163.

Datson, N.A., Morsink, M.C., Atanasova, S., Armstrong, V.W., Zischler, H., Schlumbohm, C., Dutilh, B.E., Huynen, M.A., Waegele, B., Ruepp, A., de Kloet, E.R., Fuchs, E. , Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate, BMC Genomics, vol. 8, pp. 190.

Gorter, J.A., van Vliet, E.A., Rauwerda, H., Breit, T., Stad, R., van Schaik, L., Vreugdenhil, E., Redeker, S., Hendriksen, E., Aronica, E., Lopes da Silva, F.H., Wadman, W.J. , Dynamic changes of proteases and protease inhibitors revealed by microarray analysis in CA3 and entorhinal cortex during epileptogenesis in the rat, Epilepsia, vol. 48 Suppl 5, pp. 53-64.

Vreugdenhil, E., Kolk, S.M., Boekhoorn, K., Fitzsimons, C.P., Schaaf, M.J., Schouten, T., Sarabdjitsingh, A., Sibug, R.M., Lucassen, P.J. , Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability, Eur.J.Neurosci., vol. 25, no. 3, pp. 635-648.

Zitman, F.G., Vreeburg, S., Kruijtzer, B., van Pelt, H., van Dyck, R., de Rijk, R.H., Hoogendijk, W., Penninx, B. , Depression and HPA-axis dysregulation: A large cohort study, European Psychiatry, vol. 22, pp. S25-S25.

Fink, G. , Encyclopedia of stress, , vol. 2nd: Elsevier / Academic Press.

Datson, N.A., Morsink, M.C. , Expression Profiling of Stress Responsive Gene Patterns, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 986-991.

Brinks, V., van der Mark, M.H., De Kloet, E.R., Oitzl, M.S. , Emotion and cognition in high and low stress sensitive mouse strains: a combined neuroendocrine and behavioral study in BALB/c and C57BL/6J mice, Frontiers in Behavioral Neuroscience, vol. 1, no. 8, pp. 1-12.

Vos, J.B., Datson, N.A., Rabe, K.F., Hiemstra, P.S. , Exploring host-pathogen interactions at the epithelial surface: application of transcriptomics in lung biology, Am.J.Physiol Lung Cell Mol.Physiol, vol. 292, no. 2, pp. L367-L377.

Sonneveld, E., Jonas, A., Meijer, O.C., Brouwer, A., van der Burg, B. , Glucocorticoid-Enhanced Expression of Dioxin Target Genes through Regulation of the Rat Aryl Hydrocarbon Receptor, Toxicol.Sci., vol. 99, no. 2, pp. 455-469.

van der Veen, R., Piazza, P.V., Deroche-Gamonet, V. , Gene-environment interactions in vulnerability to cocaine intravenous self-administration: a brief social experience affects intake in DBA/2J but not in C57BL/6J mice, Psychopharmacology (Berl), vol. 193, no. 2, pp. 179-186.

de Rijk, R.H., De Kloet, E.R. , Mineralocorticoid Receptor Polymorphisms, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 744-748.

Kuningas, M., de Rijk, R.H., Westendorp, R.G., Jolles, J., Slagboom, P.E., van Heemst, D. , Mental performance in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors, Neuropsychopharmacology, vol. 32, no. 6, pp. 1295-1301.

De Kloet, E.R., Rinne, T. , Neuroendocrine markers of early trauma : implications for posttraumatic stress disorders, Traumatic dissociation neurobiology and treatment, vol. 1st ed, Washington, DC, American Psychiatric Pub, pp. 139-156.

Revsin, Y., Oitzl, M.S., Saravia, F.E., De Nicola, A.E., De Kloet, E.R. , Neuroendocrine markers in streptozotocin (STZ)-induced type 1 diabetes, Diabetologia, vol. 50, pp. S282-S283, 0684.

Bemelmans, K.J., Noort, A., de Rijk, R.H., Middelkoop, H.A.M., van Kempen, G.M.J., Goekoop, J.G. , Plasma cortisol and norepinephrine in Alzheimer's disease: opposite relations with recall performance and stage of progression, Acta Neuropsychiatrica, vol. 19, no. 4, pp. 231-237.

Kap, Y.S., Hoozemans, J.J., Bodewes, A.J., Zwart, R., Meijer, O.C., Baas, F., Scheper, W. , Pin1 levels are downregulated during ER stress in human neuroblastoma cells, Neurogenetics., vol. 8, no. 1, pp. 21-27.

De Kloet, E.R. , Stress System Balance Hypothesis, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 646-650.

Helmerhorst, F.M., Sibug, R.M., De Kloet, E.R. , Stress Effect of Assisted Reproduction, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 596-598.

Karssen, A.M., De Kloet, E.R. , Synthetic Glucocorticoids, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 704-708.

Levine, S., De Kloet, E.R., Dent, G., Schmidt, M.V. , Stress Hyporesponsive Period, Encyclopedia of Stress, vol. 2nd, New York, Elsevier / Academic Press, pp. 606-611.

De Kloet, E.R. , Susceptibility or resilience to psychopathology? A question of stress, genes and balance, European Neuropsychopharmacology, vol. 17, pp. S173-S173.

Schwabe, L., Oitzl, M.S., Philippsen, C., Richter, S., Bohringer, A., Wippich, W., Schachinger, H. , Stress modulates the use of spatial versus stimulus-response learning strategies in humans, Learn.Mem., vol. 14, no. 1, pp. 109-116.

Vreugdenhil, E., de Rijk, R.H. , Stressgenen en genetische variaties: implicaties voor hersenfuncties, Neuropraxis, vol. 11, no. 3, pp. 83-89.

Van Eekelen, J.A.M., Mattes, E., Foster, J.K., De Kloet, E.R., McKeague, I.W. , The effects of HPA development on adolescent brain maturation, Early Human Development, vol. 83, pp. S122-S123, P1-140.

Veen, G., Van Vliet, I.M., de Rijk, R.H., Zitman, F.G. , The cortisol awakening response in mood, anxiety and somatoform disorders - additional impact of severity and sleep quality, European Neuropsychopharmacology, vol. 17, pp. S308-S309.

2006

van Gemert, N.G., Meijer, O.C., Morsink, M.C., Joels, M. , Effect of brief corticosterone administration on SGK1 and RGS4 mRNA expression in rat hippocampus, Stress, vol. 9, no. 3, pp. 165-70.

Schmidt, M.V., Deussing, J.M., Oitzl, M.S., Ohl, F., Levine, S., Wurst, W., Holsboer, F., Muller, M.B., de Kloet, E.R. , Differential disinhibition of the neonatal hypothalamic- pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice, Eur J Neurosci, vol. 24, no. 8, pp. 2291-8.

Lucassen, P.J., Heine, V.M., Muller, M.B., van der Beek, E.M., Wiegant, V.M., De Kloet, E.R., Joels, M., Fuchs, E., Swaab, D.F., Czeh, B. , Stress, depression and hippocampal apoptosis, CNS Neurol Disord Drug Targets, vol. 5, no. 5, pp. 531-46.

Schmidt, M.V., Levine, S., Alam, S., Harbich, D., Sterlemann, V., Ganea, K., de Kloet, E.R., Holsboer, F., Muller, M.B. , Metabolic signals modulate hypothalamic-pituitary-adrenal axis activation during maternal separation of the neonatal mouse, J Neuroendocrinol, vol. 18, no. 11, pp. 865-74.

Morsink, M.C., Joels, M., Sarabdjitsingh, R.A., Meijer, O.C., De Kloet, E.R., Datson, N.A. , The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells, J Neurochem, vol. 99, no. 4, pp. 1282-98.

Feldker, D.E., Morsink, M.C., Veenema, A.H., Datson, N.A., Proutski, V., Lathouwers, D., de Kloet, E.R., Vreugdenhil, E. , The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates, Brain Res, vol. 1089, no. 1, pp. 10-20.

van Gemert, N.G., van Riel, E., Meijer, O.C., Fehr, S., Schachner, M., Joels, M. , No effect of prolonged corticosterone over-exposure on NCAM, SGK1, and RGS4 mRNA expression in rat hippocampus, Brain Res, vol. 1093, no. 1, pp. 161-6.

Herbert, J., Goodyer, I.M., Grossman, A.B., Hastings, M.H., de Kloet, E.R., Lightman, S.L., Lupien, S.J., Roozendaal, B., Seckl, J.R. , Do corticosteroids damage the brain?, J Neuroendocrinol, vol. 18, no. 6, pp. 393-411.

Saravia, F.E., Beauquis, J., Revsin, Y., Homo-Delarche, F., de Kloet, E.R., De Nicola, A.F. , Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment, Cell Mol Neurobiol, vol. 26, no. 4-6, pp. 943-57.

de Kloet, E.R. , From punch to profile, Neurochem Res, vol. 31, no. 2, pp. 131-5.

De Rijk, R.H., Wust, S., Meijer, O.C., Zennaro, M.C., Federenko, I.S., Hellhammer, D.H., Giacchetti, G., Vreugdenhil, E., Zitman, F.G., de Kloet, E.R. , A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness, J Clin Endocrinol Metab, vol. 91, no. 12, pp. 5083-9.

Mayer, J.L., Klumpers, L., Maslam, S., de Kloet, E.R., Joels, M., Lucassen, P.J. , Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis, J Neuroendocrinol, vol. 18, no. 8, pp. 629-31.

Morsink, M.C., Steenbergen, P.J., Vos, J.B., Karst, H., Joels, M., De Kloet, E.R., Datson, N.A. , Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time, J Neuroendocrinol, vol. 18, no. 4, pp. 239-52.

Haller, J., Mikics, E., Toth, M., Halasz, J., Kruk, M.R. , Normal and abnormal aggression: human disorders and novel laboratory models, ISRA XVII World Meeting, Minneapolis, Minnesota, USA.

Vos, J.B., Datson, N.A., van Kampen, A.H., Luyf, A.C., Verhoosel, R.M., Zeeuwen, P.L., Olthuis, D., Rabe, K.F., Schalkwijk, J., Hiemstra, P.S. , A molecular signature of epithelial host defense: comparative gene expression analysis of cultured bronchial epithelial cells and keratinocytes, BMC Genomics, vol. 7, no. 1, pp. 9.

Wright, R.L., Lightner, E.N., Harman, J.S., Meijer, O.C., Conrad, C.D. , Attenuating corticosterone levels on the day of memory assessment prevents chronic stress-induced impairments in spatial memory, Eur.J.Neurosci., vol. 24, no. 2, pp. 595-605.

De Kloet, E.R., Oitzl, M.S. , Cortisol and PTSD: Animal Experiments and Clinical Perspectives, PTSD, brain mechanisms and clinical implications, New York, Springer.

Goekoop, J.G., de Winter, R.P., de Rijk, R.H., Zwinderman, K.H., Frankhuijzen-Sierevogel, A., Wiegant, V.M. , Depression with above-normal plasma vasopressin: validation by relations with family history of depression and mixed anxiety and retardation, Psychiatry Res., vol. 141, no. 2, pp. 201-211.

Steigenga, M.J., Helmerhorst, F.M., de Koning, J., Tijssen, A.M. I, Ruinard, S.A.T., Galis, F. , Evolutionary conserved structures as indicators of medical risks: increased incidence of cervical ribs after ovarian hyperstimulation in mice, Animal Biology, vol. 56, no. 1, pp. 63-68.

Jeurissen, S.M., Bogaards, J.J., Boersma, M.G., Ter Horst, J.P., Awad, H.M., Fiamegos, Y.C., van Beek, T.A., Alink, G.M., Sudholter, E.J., Cnubben, N.H., Rietjens, I.M. , Human cytochrome p450 enzymes of importance for the bioactivation of methyleugenol to the proximate carcinogen 1'-hydroxymethyleugenol, Chem.Res.Toxicol., vol. 19, no. 1, pp. 111-116.

Revsin, Y., van Wijk, D., Saravia, F.E., De Nicola, A.F., Oitzl, M.S., De Kloet, E.R. , HPA axis regulation reaches a new setpoint in acute and chronic type 1 diabetes: implications for brain pathology, Diabetologia, vol. 49, pp. 329-330.

Joels, M., Pu, Z., Wiegert, O., Oitzl, M.S., Krugers, H.J. , Learning under stress: how does it work?, Trends Cogn Sci., vol. 10, no. 4, pp. 152-158.

Hoekstra, M., Stitzinger, M., van Wanrooij, E.J., Michon, I.N., Kruijt, J.K., Kamphorst, J., Van Eck, M., Vreugdenhil, E., Van Berkel, T.J., Kuiper, J. , Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet, J.Lipid Res., vol. 47, no. 10, pp. 2198-2207.

De Kloet, E.R. , Neurodevelopmental setpoint and vulnerability to disease, European Neuropsychopharmacology, vol. 16, pp. S202-S202.

Haller, J., Kruk, M.R. , Normal and abnormal aggression: human disorders and novel laboratory models, Neurosci.Biobehav.Rev., vol. 30, no. 3, pp. 292-303.

de Rijk, R.H., De Kloet, E.R. , Stress, glucocorticoids, and the brain, Nutrients, stress, and medical disorders, Totowa, N.J, Humana Press, pp. 111-135.

de Jong, I.E.M., van den Buuse, M. , SCH 23390 in the prefrontal cortex enhances the effect of apomorphine on prepulse inhibition of rats, Neuropharmacology, vol. 51, no. 3, pp. 438-446.

De Kloet, E.R., Sibug, R.M., Helmerhorst, F.M., Schmidt, M.V. , Stress, genes and the mechanism of programming the brain for later life (vol 29, pg 271, 2005), Neuroscience and Biobehavioral Reviews, vol. 30, no. 4, pp. 576-576.

Meijer, O.C., van der Laan, S., Lachize, S., Steenbergen, P.J., de Kloet, E.R. , Steroid receptor coregulator diversity: what can it mean for the stressed brain?, Neuroscience, vol. 138, no. 3, pp. 891-9.

Schmidt, M.V., Enthoven, L., van der Mark, M.H., Levine, S., De Kloet, E.R., Oitzl, M.S. , The postnatal development of the hypothalamic-pituitary-adrenal axis in the mouse (vol 23, pg 125, 2003), International Journal of Developmental Neuroscience, vol. 24, no. 4, pp. 293-293.

van Leeuwen, N., Wust, S., Meijer, O.C., De Kloet, E.R., Zitman, F.G., de Rijk, R.H. , The role of single nucleotide polymorphisms (SNPs) in the mineralocorticoid receptor (MR) in stress response and psychopathology, American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, vol. 141B, no. 7, pp. 752-752.

Meijer, O.C. , Understanding stress through the genome, Stress, vol. 9, no. 2, pp. 61-67.

2005

van der Laan, S., Lachize, S.B., Schouten, T.G., Vreugdenhil, E., de Kloet, E.R., Meijer, O.C. , Neuroanatomical distribution and colocalisation of nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid receptors (SMRT) in rat brain, Brain Res, vol. 1059, no. 2, pp. 113-21.

Revsin, Y., Saravia, F., Roig, P., Lima, A., de Kloet, E.R., Homo-Delarche, F., De Nicola, A.F. , Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes, Brain Res, vol. 1038, no. 1, pp. 22-31.

Schmidt, M.V., Levine, S., Oitzl, M.S., van der Mark, M., Muller, M.B., Holsboer, F., de Kloet, E.R. , Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse, Endocrinology, vol. 146, no. 3, pp. 1458-64.

Meijer, O.C., Kalkhoven, E., van der Laan, S., Steenbergen, P.J., Houtman, S.H., Dijkmans, T.F., Pearce, D., de Kloet, E.R. , Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling, Endocrinology, vol. 146, no. 3, pp. 1438-48.

Sibug, R.M., de Koning, J., Tijssen, A.M., de Ruiter, M.C., de Kloet, E.R., Helmerhorst, F.M. , Urinary gonadotrophins but not recombinant gonadotrophins reduce expression of VEGF120 and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period, Hum Reprod, vol. 20, no. 3, pp. 649-56.

de Kloet, E.R., Joels, M., Holsboer, F. , Stress and the brain: from adaptation to disease, Nat Rev Neurosci, vol. 6, no. 6, pp. 463-75.

Veenema, A.H., Sijtsma, B., Koolhaas, J.M., de Kloet, E.R. , The stress response to sensory contact in mice: genotype effect of the stimulus animal, Psychoneuroendocrinology, vol. 30, no. 6, pp. 550-7.

De Rijk, R.H., de Kloet, E.R. , Corticosteroid receptor genetic polymorphisms and stress responsivity, Endocrine, vol. 28, no. 3, pp. 263-70.

Karssen, A.M., Meijer, O.C., Berry, A., Sanjuan Pinol, R., de Kloet, E.R. , Low doses of dexamethasone can produce a hypocorticosteroid state in the brain, Endocrinology, vol. 146, no. 12, pp. 5587-95.

de Kloet, E.R., Sibug, R.M., Helmerhorst, F.M., Schmidt, M.V. , Stress, genes and the mechanism of programming the brain for later life, Neurosci Biobehav Rev, vol. 29, no. 2, pp. 271-81.

Dalm, S., Enthoven, L., Meijer, O.C., van der Mark, M.H., Karssen, A.M., de Kloet, E.R., Oitzl, M.S. , Age-related changes in hypothalamic-pituitary-adrenal axis activity of male C57BL/6J mice, Neuroendocrinology, vol. 81, no. 6, pp. 372-80.

Wust, S., de Rijk, R.H., Meijer, O.C., Federenko, I, Vreugdenhil, E., de Punder, K., Hellhammer, D., De Kloet, E.R. , A common mineralocorticoid receptor gene variant is associated with cortisol and heart rate response to psychosocial stress, Journal of Psychophysiology, vol. 19, no. 2, pp. 154-155.

Meijer, O.C., Topic, B., Steenbergen, P.J., Jocham, G., Huston, J.P., Oitzl, M.S. , Correlations between hypothalamus-pituitary-adrenal axis parameters depend on age and learning capacity, Endocrinology, vol. 146, no. 3, pp. 1372-1381.

Champagne, D.L., Rochford, J., Poirier, J. , Effect of apolipoprotein E deficiency on reactive sprouting in the dentate gyrus of the hippocampus following entorhinal cortex lesion: role of the astroglial response, Exp Neurol., vol. 194, no. 1, pp. 31-42.

Engels, B.M. , Expression and functional characterization of DoubleCortin-Like Kinase (DCLK) splice variants, , vol. PhD: Leiden University.

Kruk, M.R., De Kloet, E.R. , Genen, glucocortico‹den en geweld, Tijdschrift voor Criminologie, vol. 47, no. 2, pp. 136-141.

Revsin, Y., Dalm, S., Saravia, F.E., Oitzl, M.S., De Nicola, A.F., De Kloet, E.R. , HPA axis regulation in type 1 diabetes, Diabetologia, vol. 48, pp. A234-A234.

Ingram, N., Martin, S., Wang, J.H., van der Laan, S., Loiacono, R., van den Buuse, M. , Interaction of corticosterone and nicotine in regulation of prepulse inhibition in mice, Neuropharmacology, vol. 48, no. 1, pp. 80-92.

Hrabovszky, E., Halasz, J., Meelis, W., Kruk, M.R., Liposits, Z., Haller, J. , Neurochemical characterization of hypothalamic neurons involved in attack behavior: glutamatergic dominance and co-expression of thyrotropin-releasing hormone in a subset of glutamatergic neurons, Neuroscience, vol. 133, no. 3, pp. 657-666.

Schmidt, M.V., Oitzl, M.S., Muller, M.B., Ohl, F., Wurst, W., Holsboer, F., Levine, S., De Kloet, E.R. , Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice (vol 119, pg 589, 2003), Neuroscience, vol. 135, no. 4, pp. 1343-1343.

De Kloet, E.R. , Stress, cortisol and cognition: Towards understanding a vulnerable phenotype for stress-related psychopathology, Nordic Journal of Psychiatry, vol. 59, no. 5, pp. 398-398.

Oitzl, M.S., Enthoven, L., De Kloet, E.R. , Stress system regulation, glucocorticoid receptors and traumatic early life events, European Psychiatry, vol. 20, no. Suppl-1, pp. S102-S102.

Schmidt, M.V., Oitzl, M.S., Levine, S., De Kloet, E.R. , The HPA system during the postnatal development of CD1 mice and the effects of maternal deprivation (vol 139, pg 39, 2002), Developmental Brain Research, vol. 160, no. 2, pp. 287-287.

Vos, J.B., van Sterkenburg, M.A., Rabe, K.F., Schalkwijk, J., Hiemstra, P.S., Datson, N.A. , Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense, Physiol Genomics, vol. 21, no. 3, pp. 324-336.

van Overveld, P.G., Enthoven, L., Ricci, E., Rossi, M., Felicetti, L., Jeanpierre, M., Winokur, S.T., Frants, R.R., Padberg, G.W., van der Maarel, S.M. , Variable hypomethylation of D4Z4 in facioscapulohumeral muscular dystrophy, Ann.Neurol., vol. 58, no. 4, pp. 569-576.

2004

Datson, N.A., Meijer, L., Steenbergen, P.J., Morsink, M.C., van der Laan, S., Meijer, O.C., de Kloet, E.R. , Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression, Eur J Neurosci, vol. 20, no. 10, pp. 2541-54.

Veenema, A.H., Koolhaas, J.M., de Kloet, E.R. , Basal and stress-induced differences in HPA axis, 5-HT responsiveness, and hippocampal cell proliferation in two mouse lines, Ann N Y Acad Sci, vol. 1018, pp. 255-65.

de Jong, I.E., de Kloet, E.R. , Glucocorticoids and vulnerability to psychostimulant drugs: toward substrate and mechanism, Ann N Y Acad Sci, vol. 1018, pp. 192-8.

De Kloet, E.R. , Hormones and the stressed brain, Ann N Y Acad Sci, vol. 1018, pp. 1-15.

van Riel, E., van Gemert, N.G., Meijer, O.C., Joels, M. , Effect of early life stress on serotonin responses in the hippocampus of young adult rats, Synapse, vol. 53, no. 1, pp. 11-19.

Grootendorst, J., Enthoven, L., Dalm, S., de Kloet, E.R., Oitzl, M.S. , Increased corticosterone secretion and early-onset of cognitive decline in female apolipoprotein E-knockout mice, Behav Brain Res, vol. 148, no. 1-2, pp. 167-77.

Schmidt, M.V., Enthoven, L., van Woezik, J.H., Levine, S., de Kloet, E.R., Oitzl, M.S. , The dynamics of the hypothalamic-pituitary-adrenal axis during maternal deprivation, J Neuroendocrinol, vol. 16, no. 1, pp. 52-7.

Karssen, A.M., Meijer, O., Pons, D., De Kloet, E.R. , Localization of mRNA expression of P-glycoprotein at the blood-brain barrier and in the hippocampus, Ann N Y Acad Sci, vol. 1032, pp. 308-11.

De Kloet, E.R., De Rijk, R.H. , Signaling pathways in brain involved in predisposition and pathogenesis of stress-related disease: genetic and kinetic factors affecting the MR/GR balance, Ann N Y Acad Sci, vol. 1032, pp. 14-34.

Enthoven, L., Dalm, S., de Kloet, E.R., Oitzl, M.S. , Swim posture of mice does not affect performance in the water maze, Brain Res, vol. 1003, no. 1-2, pp. 36-41.

Kruk, M.R., Halasz, J., Mikics, E., Meelis, W., Haller, J. , Corticosteroid Feedback to the Brain Tips the Flight-Fight Balance in the Brain towards Aggression, ISRA XVI World Meeting, Santorini, Greece.

De Kloet, E.R., de Kloet, S.R. , Analysis of the beak and feather disease viral genome indicates the existence of several genotypes which have a complex psittacine host specificity, Arch.Virol., vol. 149, no. 12, pp. 2393-2412.