Recent publications

2010

Schenk, G.J., Werkman, T., Wadman, W., Veldhuisen, B., Dijkmans, T.F., Blaas, E., Kegel, L., de Kloet, E.R., Vreugdenhil, E. , Over-expression of the DCLK gene transcript CARP decreases CA3/CA1 network excitability, Brain Res, vol. 1352C, pp. 21-34.

Schwabe, L., Schachinger, H., de Kloet, E.R., Oitzl, M.S. , Stress impairs spatial but not early stimulus-response learning, Behav Brain Res, vol. 213, no. 1, pp. 50-5.

Sarabdjitsingh, R.A., Meijer, O.C., de Kloet, E.R. , Specificity of glucocorticoid receptor primary antibodies for analysis of receptor localization patterns in cultured cells and rat hippocampus, Brain Res, vol. 1331, pp. 1-11.

Oitzl, M.S., Champagne, D.L., van der Veen, R., de Kloet, E.R. , Brain development under stress: hypotheses of glucocorticoid actions revisited, Neurosci Biobehav Rev, vol. 34, no. 6, pp. 853-66.

Berry, A., Carnevale, D., Giorgio, M., Pelicci, P.G., de Kloet, E.R., Alleva, E., Minghetti, L., Cirulli, F. , Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice, Exp Gerontol, vol. 45, no. 5, pp. 343-50.

Sarabdjitsingh, R.A., Isenia, S., Polman, A., Mijalkovic, J., Lachize, S., Datson, N., de Kloet, E.R., Meijer, O.C. , Disrupted corticosterone pulsatile patterns attenuate responsiveness to glucocorticoid signaling in rat brain, Endocrinology, vol. 151, no. 3, pp. 1177-86.

Dijkmans, T.F., van Hooijdonk, L.W., Fitzsimons, C.P., Vreugdenhil, E. , The doublecortin gene family and disorders of neuronal structure, Cent Nerv Syst Agents Med Chem, vol. 10, no. 1, pp. 32-46.

Conway-Campbell, B.L., Sarabdjitsingh, R.A., McKenna, M.A., Pooley, J.R., Kershaw, Y.M., Meijer, O.C., de Kloet, E.R., Lightman, S.L. , Glucocorticoid ultradian rhythmicity directs cyclical gene pulsing of the Clock gene Period 1 in rat hippocampus, J Neuroendocrinol.

Schwabe, L., Schachinger, H., de Kloet, E.R., Oitzl, M.S. , Corticosteroids operate as a switch between memory systems, J Cogn Neurosci, vol. 22, no. 7, pp. 1362-72.

de Kloet, E.R. , From vasotocin to stress and cognition, Eur J Pharmacol, vol. 626, no. 1, pp. 18-26.

Richter, S., Schulz, A., Zech, C.M., Oitzl, M.S., Daskalakis, N.P., Blumenthal, T.D., Schachinger, H. , Cortisol rapidly disrupts prepulse inhibition in healthy men, Psychoneuroendocrinology.

Schenk, G.J., Veldhuisen, B., Wedemeier, O., McGown, C.C., Schouten, T.G., Oitzl, M., de Kloet, E.R., Vreugdenhil, E. , Over-expression of deltaC-DCLK-short in mouse brain results in a more anxious behavioral phenotype, Physiol Behav.

van Leeuwen, N., Kumsta, R., Entringer, S., de Kloet, E.R., Zitman, F.G., De Rijk, R.H., Wust, S. , Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone, Psychoneuroendocrinology, vol. 35, no. 3, pp. 339-49.

Enthoven, L., Schmidt, M.V., Cheung, Y.H., van der Mark, M.H., de Kloet, E.R., Oitzl, M.S. , Ontogeny of the HPA axis of the CD1 mouse following 24 h maternal deprivation at pnd 3, Int J Dev Neurosci, vol. 28, no. 2, pp. 217-24.

Berry, A. , Oxidative stress, neuroendocrine function and behavior in an animal model of extended longevity, , vol. PhD: Leiden University.

van Hooijdonk, L.W.A. , Glucocorticoid receptor knockdown and adult hippocampal neurogenesis, , vol. PhD: Leiden University.

Sarabdjitsingh, R.A. , Glucocorticoid pulsatility : implications for brain functioning, , vol. PhD: Leiden University.

de Backer, M.W., Fitzsimons, C.P., Brans, M.A., Luijendijk, M.C., Garner, K.M., Vreugdenhil, E., Adan, R.A. , An adeno-associated viral vector transduces the rat hypothalamus and amygdala more efficient than a lentiviral vector, BMC Neurosci, vol. 11, pp. 81.

Rouwette, T.P., Kozicz, T., Olde Loohuis, N.F., Gaszner, B., Vreugdenhil, E., Scheffer, G.J., Roubos, E.W., Vissers, K.C., Scheenen, W.J. , Acute Pain Increases Phosphorylation of DCLK-Long in the Edinger-Westphal Nucleus but not in the Hypothalamic Paraventricular Nucleus of the Rat, J.Pain.

Alt, S.R., Turner, J.D., Klok, M.D., Meijer, O.C., Lakke, E.A., de Rijk, R.H., Muller, C.P. , Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed, Psychoneuroendocrinology, vol. 35, no. 4, pp. 544-556.

Bohnke, R., Bertsch, K., Kruk, M.R., Richter, S., Naumann, E. , Exogenous cortisol enhances aggressive behavior in females, but not in males, Psychoneuroendocrinology.

Jacobs, G.E., Kamerling, I.M., de Kam, M.L., de Rijk, R.H., van Pelt, J., Zitman, F.G., Van Gerven, J.M. , Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron, J.Psychopharmacol., vol. 24, no. 1, pp. 65-72.

Tubio, M.R., Fernandez, N., Fitzsimons, C.P., Copsel, S., Santiago, S., Shayo, C., Davio, C., Monczor, F. , Expression of a G protein-coupled receptor (GPCR) leads to attenuation of signaling by other GPCRs: experimental evidence for a spontaneous GPCR constitutive inactive form, J.Biol.Chem., vol. 285, no. 20, pp. 14990-14998.

Vreugdenhil, E., Berezikov, E. , Fine-tuning the brain: MicroRNAs, Front Neuroendocrinol., vol. 31, no. 2, pp. 128-133.

Licht, C.M., Vreeburg, S.A., van Reedt Dortland, A.K., Giltay, E.J., Hoogendijk, W.J., de Rijk, R.H., Vogelzangs, N., Zitman, F.G., de Geus, E.J., Penninx, B.W. , Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalities, J.Clin.Endocrinol.Metab, vol. 95, no. 5, pp. 2458-2466.

Qiu, S., Champagne, D.L., Peters, M., Catania, E.H., Weeber, E.J., Levitt, P., Pimenta, A.F. , Loss of Limbic System-Associated Membrane Protein Leads to Reduced Hippocampal Mineralocorticoid Receptor Expression, Impaired Synaptic Plasticity, and Spatial Memory Deficit, Biol.Psychiatry.

Schwabe, L., Wolf, O.T., Oitzl, M.S. , Memory formation under stress: quantity and quality, Neurosci.Biobehav.Rev., vol. 34, no. 4, pp. 584-591.

Bosker, F.J., Hartman, C.A., Nolte, I.M., Prins, B.P., Terpstra, P., Posthuma, D., van Veen, T., Willemsen, G., de Rijk, R.H., de Geus, E.J., Hoogendijk, W.J., Sullivan, P.F., Penninx, B.W., Boomsma, D. I, Snieder, H., Nolen, W.A. , Poor replication of candidate genes for major depressive disorder using genome-wide association data, Mol.Psychiatry.

Van Batenburg, M.F., Li, H., Polman, J.A., Lachize, S., Datson, N.A., Bussemaker, H.J., Meijer, O.C. , Paired hormone response elements predict caveolin-1 as a glucocorticoid target gene, PLoS One, vol. 5, no. 1, pp. e8839.

Sarabdjitsingh, R.A., Spiga, F., Oitzl, M.S., Kershaw, Y., Meijer, O.C., Lightman, S.L., De Kloet, E.R. , Recovery from disrupted ultradian glucocorticoid rhythmicity reveals a dissociation between hormonal and behavioral stress responsiveness, J.Neuroendocrinol..

Verissimo, C.S., Molenaar, J.J., Meerman, J., Puigvert, J.C., Lamers, F., Koster, J., Danen, E.H., van de Water, B., Versteeg, R., Fitzsimons, C.P., Vreugdenhil, E. , Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells, Endocr.Relat Cancer, vol. 17, no. 2, pp. 399-414.

Vreeburg, S.A., Zitman, F.G., van Pelt, J., de Rijk, R.H., Verhagen, J.C., van Dyck, R., Hoogendijk, W.J., Smit, J.H., Penninx, B.W. , Salivary cortisol levels in persons with and without different anxiety disorders, Psychosom.Med., vol. 72, no. 4, pp. 340-347.

Bohnke, R., Bertsch, K., Kruk, M.R., Naumann, E. , The relationship between basal and acute HPA axis activity and aggressive behavior in adults, J.Neural Transm., vol. 117, no. 5, pp. 629-637.

Murphy, K.J., Ter Horst, J.P., Cassidy, A.W., DeSouza, I.E., Morgunova, M., Li, C., Connole, L.M., O'Sullivan, N.C., Loscher, J.S., Brady, A.T., Rombach, N., Connellan, J., McGettigan, P.A., Scully, D., Fedriani, R., Lukasz, B., Moran, M.P., McCabe, O.M., Wantuch, C.M., Hughes, Z.A., Mulvany, S.K., Higgins, D.G., Pangalos, M.N., Marquis, K.L., O'Connor, W.T., Ring, R.H., von Schack, D., Regan, C.M. , Temporal dysregulation of cortical gene expression in the isolation reared Wistar rat, J.Neurochem., vol. 113, no. 3, pp. 601-614.

2009

de Kloet, E.R., Fitzsimons, C.P., Datson, N.A., Meijer, O.C., Vreugdenhil, E. , Glucocorticoid signaling and stress-related limbic susceptibility pathway: about receptors, transcription machinery and microRNA, Brain Res, vol. 1293, pp. 129-41.

Jud, C., Chappuis, S., Revell, V.L., Sletten, T.L., Saaltink, D.J., Cajochen, C., Skene, D.J., Albrecht, U. , Age-dependent alterations in human PER2 levels after early morning blue light exposure, Chronobiol Int, vol. 26, no. 7, pp. 1462-9.

van Gemert, N.G., Carvalho, D.M., Karst, H., van der Laan, S., Zhang, M., Meijer, O.C., Hell, J.W., Joels, M. , Dissociation between rat hippocampal CA1 and dentate gyrus cells in their response to corticosterone: effects on calcium channel protein and current, Endocrinology, vol. 150, no. 10, pp. 4615-24.

van Veen, J.F., van Vliet, I.M., de Rijk, R.H., van Pelt, J., Mertens, B., Fekkes, D., Zitman, F.G. , Tryptophan depletion affects the autonomic stress response in generalized social anxiety disorder, Psychoneuroendocrinology, vol. 34, no. 10, pp. 1590-4.

Lachize, S., Apostolakis, E.M., van der Laan, S., Tijssen, A.M., Xu, J., de Kloet, E.R., Meijer, O.C. , Steroid receptor coactivator-1 is necessary for regulation of corticotropin-releasing hormone by chronic stress and glucocorticoids, Proc Natl Acad Sci U S A, vol. 106, no. 19, pp. 8038-42.

Vreugdenhil, E., Verissimo, C.S., Mariman, R., Kamphorst, J.T., Barbosa, J.S., Zweers, T., Champagne, D.L., Schouten, T., Meijer, O.C., de Kloet, E.R., Fitzsimons, C.P. , MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain, Endocrinology, vol. 150, no. 5, pp. 2220-8.

Champagne, D.L., de Kloet, E.R., Joels, M. , Fundamental aspects of the impact of glucocorticoids on the (immature) brain, Semin Fetal Neonatal Med, vol. 14, no. 3, pp. 136-42.

de Jong, I.E., Steenbergen, P.J., de Kloet, E.R. , Behavioral sensitization to cocaine: cooperation between glucocorticoids and epinephrine, Psychopharmacology (Berl), vol. 204, no. 4, pp. 693-703.

Dijkmans, T.F., van Hooijdonk, L.W., Schouten, T.G., Kamphorst, J.T., Fitzsimons, C.P., Vreugdenhil, E. , Identification of new Nerve Growth Factor-responsive immediate-early genes, Brain Res, vol. 1249, pp. 19-33.

Sarabdjitsingh, R.A., Meijer, O.C., Schaaf, M.J., de Kloet, E.R. , Subregion-specific differences in translocation patterns of mineralocorticoid and glucocorticoid receptors in rat hippocampus, Brain Res, vol. 1249, pp. 43-53.

Natarajan, D., de Vries, H., Saaltink, D.J., de Boer, S.F., Koolhaas, J.M. , Delineation of violence from functional aggression in mice: an ethological approach, Behav Genet, vol. 39, no. 1, pp. 73-90.

de Jong, I.E., de Kloet, E.R. , Critical time-window for the actions of adrenal glucocorticoids in behavioural sensitisation to cocaine, Eur J Pharmacol, vol. 604, no. 1-3, pp. 66-73.

Fitzsimons, C.P., van Hooijdonk, L.W., Morrow, J.A., Peeters, B.W., Hamilton, N., Craighead, M., Vreugdenhil, E. , Antiglucocorticoids, neurogenesis and depression, Mini Rev Med Chem, vol. 9, no. 2, pp. 249-64.

Revsin, Y., Rekers, N.V., Louwe, M.C., Saravia, F.E., De Nicola, A.F., de Kloet, E.R., Oitzl, M.S. , Glucocorticoid receptor blockade normalizes hippocampal alterations and cognitive impairment in streptozotocin-induced type 1 diabetes mice, Neuropsychopharmacology, vol. 34, no. 3, pp. 747-58.

Daskalakis, N.P., Kaperoni, M., Koros, C., de Kloet, E.R., Kitraki, E. , Environmental and tactile stimulation modulates the neonatal handling effect on adult rat spatial memory, Int J Dev Neurosci, vol. 27, no. 8, pp. 747-55.

Datson, N.A., Morsink, M.C., Steenbergen, P.J., Aubert, Y., Schlumbohm, C., Fuchs, E., de Kloet, E.R. , A molecular blueprint of gene expression in hippocampal subregions CA1, CA3, and DG is conserved in the brain of the common marmoset, Hippocampus, vol. 19, no. 8, pp. 739-52.

Brinks, V., Berger, S., Gass, P., de Kloet, E.R., Oitzl, M.S. , Mineralocorticoid receptors in control of emotional arousal and fear memory, Horm Behav, vol. 56, no. 2, pp. 232-8.

Brinks, V., de Kloet, E.R., Oitzl, M.S. , Corticosterone facilitates extinction of fear memory in BALB/c mice but strengthens cue related fear in C57BL/6 mice, Exp Neurol, vol. 216, no. 2, pp. 375-82.

Brinks, V. , Stress, emotion and cognition : role of mineralo- and glucocorticoid receptors, , vol. PhD: Leiden University.

Dijkmans, T.F. , Doublecortin-like kinase and neuronal differentiation, , vol. PhD: Leiden University.

Vreeburg, S.A., Kruijtzer, B.P., van Pelt, J., van Dyck, R., de Rijk, R.H., Hoogendijk, W.J., Smit, J.H., Zitman, F.G., Penninx, B.W. , Associations between sociodemographic, sampling and health factors and various salivary cortisol indicators in a large sample without psychopathology, Psychoneuroendocrinology, vol. 34, no. 8, pp. 1109-1120.

Alvarez, E.O., Beauquis, J., Revsin, Y., Banzan, A.M., Roig, P., De Nicola, A.F., Saravia, F. , Cognitive dysfunction and hippocampal changes in experimental type 1 diabetes, Behav.Brain Res., vol. 198, no. 1, pp. 224-230.

Boer, K., Lucassen, P.J., Spliet, W.G., Vreugdenhil, E., van Rijen, P.C., Troost, D., Jansen, F.E., Aronica, E. , Doublecortin-like (DCL) expression in focal cortical dysplasia and cortical tubers, Epilepsia.

Spijker, A.T., van Rossum, E.F., Hoencamp, E., de Rijk, R.H., Haffmans, J., Blom, M., Manenschijn, L., Koper, J.W., Lamberts, S.W., Zitman, F.G. , Functional polymorphism of the glucocorticoid receptor gene associates with mania and hypomania in bipolar disorder, Bipolar.Disord., vol. 11, no. 1, pp. 95-101.

Langemeijer, E., Maussang, D., Fitzsimons, C.P., Dijkman, R., Stigter-van Walsum, M., Tensen, C.P., van Dongen, G.A., Michel, D., Leurs, R., Smit, M.J. , Hcmv-Encoded Chemokine Receptor Us28 Modulates Oncogenic Gene Networks; A Role for Cox-2 in Us28-Mediated Tumor Formation, Naunyn-Schmiedebergs Archives of Pharmacology, vol. 380, no. 3, pp. 261-261.

Bertsch, K., Böhnke, R., Kruk, M.R., Naumann, E. , Influence of aggression on information processing in the emotional Stroop task - an event-related potential study, Front.Behav.Neurosci., vol. 3, no. 28, pp. 1-20.

Smit-Rigter, L.A., Champagne, D.L., van Hooft, J.A. , Lifelong impact of variations in maternal care on dendritic structure and function of cortical layer 2/3 pyramidal neurons in rat offspring, PLoS.ONE., vol. 4, no. 4, pp. e5167.

van Hooijdonk, L.W., Ichwan, M., Dijkmans, T.F., Schouten, T.G., de Backer, M.W., Adan, R.A., Verbeek, F.J., Vreugdenhil, E., Fitzsimons, C.P. , Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression, BMC Neurosci, vol. 10, pp. 2.

Bagot, R.C., van Hasselt, F.N., Champagne, D.L., Meaney, M.J., Krugers, H.J., Joels, M. , Maternal care determines rapid effects of stress mediators on synaptic plasticity in adult rat hippocampal dentate gyrus, Neurobiol.Learn.Mem..

Schwabe, L., Oitzl, M.S., Richter, S., Schachinger, H. , Modulation of spatial and stimulus-response learning strategies by exogenous cortisol in healthy young women, Psychoneuroendocrinology, vol. 34, no. 3, pp. 358-366.

Vreeburg, S.A., Hoogendijk, W.J., van Pelt, J., de Rijk, R.H., Verhagen, J.C., van Dyck, R., Smit, J.H., Zitman, F.G., Penninx, B.W. , Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study, Arch.Gen.Psychiatry, vol. 66, no. 6, pp. 617-626.

De Kloet, E.R. , Neuroendocrine Aging: Pituitary-Adrenal Axis, Encyclopedia of Neuroscience, Oxford, Academic Press, pp. 309-315.

Dalm, S., Schwabe, L., Schachinger, H., Oitzl, M.S. , Post-training self administration of sugar facilitates cognitive performance of male C57BL/6J mice in two spatial learning tasks, Behav.Brain Res., vol. 198, no. 1, pp. 98-104.

Dalm, S., de Visser, L., Spruijt, B.M., Oitzl, M.S. , Repeated rat exposure inhibits the circadian activity patterns of C57BL/6J mice in the home cage, Behav.Brain Res., vol. 196, no. 1, pp. 84-92.

Ambroggi, F., Turiault, M., Milet, A., roche-Gamonet, V., Parnaudeau, S., Balado, E., Barik, J., van der Veen, R., Maroteaux, G., Lemberger, T., Schutz, G., Lazar, M., Marinelli, M., Piazza, P.V., Tronche, F. , Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking, Nature Neuroscience, vol. 12, no. 3, pp. 247-249.

de Kloet, E.R. , Stress: a neurobiological perspective, Tijdschr Psychiatr, vol. 51, no. 8, pp. 541-50.

de Rijk, R.H. , Single nucleotide polymorphisms related to HPA axis reactivity, Neuroimmunomodulation., vol. 16, no. 5, pp. 340-352.

Veen, G., Giltay, E.J., de Rijk, R.H., van Vliet, I, van Pelt, J., Zitman, F.G. , Salivary cortisol, serum lipids, and adiposity in patients with depressive and anxiety disorders, Metabolism, vol. 58, no. 6, pp. 821-827.

Bertsch, K., Khan, R., Kruk, M.R., Richter, S., Naumann, E. , The Influence of Cortisol and Aggression on the Processing of Emotional Facial Expressions, Psychophysiology, vol. 46, pp. S25-S25.

Bertsch, K., Trenz, J., Khan, R., Kruk, M.R., Richter, S., Naumann, E. , The Influence of Trait Anger, Cortisol, and Aggression Resting Cortical Activity, Psychophysiology, vol. 46, pp. S50-S50.

Khan, R., Bender, A., Bertsch, K., Kruk, M.R., Richter, S., Naumann, E. , The Relationship of Aggressive Behavior to Cardiovascular and HPA Axis Activity, Psychophysiology, vol. 46, pp. S123-S123.

Maussang, D., Langemeijer, E., Fitzsimons, C.P., Stigter-van Walsum, M., Dijkman, R., Borg, M.K., Slinger, E., Schreiber, A., Michel, D., Tensen, C.P., van Dongen, G.A., Leurs, R., Smit, M.J. , The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2, Cancer Res., vol. 69, no. 7, pp. 2861-2869.

van der Laan, S., de Kloet, E.R., Meijer, O.C. , Timing is critical for effective glucocorticoid receptor mediated repression of the cAMP-induced CRH gene, PLoS One, vol. 4, no. 1, pp. e4327.

Veen, G., de Rijk, R.H., Giltay, E.J., van Vliet, I, van Pelt, J., Zitman, F.G. , The influence of psychiatric comorbidity on the dexamethasone/CRH test in major depression, Eur.Neuropsychopharmacol., vol. 19, no. 6, pp. 409-415.

Revsin, Y., de Kloet, E.R. , When glucocorticoids change from protective to harmful. Lessons from a type 1 diabetes animal model, Medicina (B Aires), vol. 69, no. 3, pp. 353-8.

Brittijn, S.A., Duivesteijn, S.J., Belmamoune, M., Bertens, L.F., Bitter, W., de Bruijn, J.D., Champagne, D.L., Cuppen, E., Flik, G., Vandenbroucke-Grauls, C.M., Janssen, R.A., de Jong, I.M., de Kloet, E.R., Kros, A., Meijer, A.H., Metz, J.R., van der Sar, A.M., Schaaf, M.J., Schulte-Merker, S., Spaink, H.P., Tak, P.P., Verbeek, F.J., Vervoordeldonk, M.J., Vonk, F.J., Witte, F., Yuan, H., Richardson, M.K. , Zebrafish development and regeneration: new tools for biomedical research, Int J Dev Biol, vol. 53, no. 5-6, pp. 835-50.

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